Migrating Swollen Joint and Lyme Disease: A Case Report

This article discusses a case involving a pediatric patient who presented to a large urban children's hospital in the Northeastern United States with complaints of migratory monoarticular joint swelling. The patient had presented with a swollen and painful left knee but with no other associated symptoms. He was nontoxic appearing, afebrile, and had normal vital signs. On examination, he was noted to have a tender and swollen left knee that was not erythematous, bruised, or warm to the touch. There was a history of fevers over the summer after returning home from a camping trip in a park located in the Northeastern United States.
Source: Journal of Emergency Nursing: JEN - Category: Nursing Authors: Tags: Case Review Source Type: research

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Dr. Auwaerter has consulted for DiaSorin, Adaptive Biotherapeutics and Pfizer; has done research sponsored by MicroB-Plex; has been an expert witness in malpractice cases involving Lyme disease; and is an unpaid board member of the American Lyme Disease Foundation. Dr. Kobayashi has no disclosures. Dr. Wormser reports receiving research grants from the Institute for Systems Biology and Pfizer, Inc. He has been an expert witness in malpractice cases involving Lyme disease; and is an unpaid board member of the non-profit American Lyme Disease Foundation.
Source: The American Journal of Medicine - Category: General Medicine Authors: Source Type: research
OBJECTIVE: Lyme borreliosis is a tick-borne infectious disease that may confer an increased risk of mental disorders, but previous studies have been hampered by methodological limitations, including small sample sizes. The authors used a nationwide retrosp...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
People in Denmark diagnosed with Lyme disease in a hospital went on to have 28% higher rates of mental disorders and were twice as likely to have attempted suicide, compared with those without the diagnosis, according to astudy published Wednesday inAJP in Advance. Having more than one episode of Lyme disease was associated with a higher rate of mental disorders, affective disorders, and suicide attempts.According to theCDC, nearly half a million people a year in the United States are treated for Lyme disease (also known as Lyme borreliosis), the most common vector-borne disease, and the areas where Lyme disease is common ...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance CDC Denmark hospitalized infections lyme disease mental disorders suicide Source Type: research
CONCLUSIONS: Individuals diagnosed with Lyme borreliosis in the hospital setting had an increased risk of mental disorders, affective disorders, suicide attempts, and suicide. Although the absolute population risk is low, clinicians should be aware of potential psychiatric sequelae of this global disease.PMID:34315282 | DOI:10.1176/appi.ajp.2021.20091347
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research
The high polymorphism of Major Histocompatibility Complex (MHC) genes is generally considered to be a result of pathogen-mediated balancing selection. Such selection may operate in the form of heterozygote advantage, and/or through specific MHC allele–pathogen interactions. Specific MHC allele–pathogen interactions may promote polymorphism via negative frequency-dependent selection (NFDS), or selection that varies in time and/or space because of variability in the composition of the pathogen community (fluctuating selection; FS). In addition, divergent allele advantage (DAA) may act on top of these forms of bal...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
SUNDAY, July 25, 2021 -- When you're heading outdoors this summer, keep an eye out for ticks during and after your outing, health experts say. These common parasites can transmit Lyme disease, a potentially serious illness. Lyme disease is...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Immunobiology. 2021 Jul 13;226(5):152091. doi: 10.1016/j.imbio.2021.152091. Online ahead of print.ABSTRACTThe spike protein of coronavirus is key target for drug development and other pharmacological interventions. In current study, we performed an integrative approach to predict antigenic sites in SARS-CoV-2 spike receptor binding domain and found nine potential antigenic sites. The predicted antigenic sites were then assessed for possible molecular similarity with other known antigens in different organisms. Out of nine sites, seven sites showed molecular similarity with 54 antigenic determinants found in twelve pathogen...
Source: Immunobiology - Category: Allergy & Immunology Authors: Source Type: research
Source: Neuro-Ophthalmology - Category: Opthalmology Authors: Source Type: research
J Vector Borne Dis. 2020 Apr-Jun;57(2):189-192. doi: 10.4103/0972-9062.310870.NO ABSTRACTPMID:34290166 | DOI:10.4103/0972-9062.310870
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research
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