Outcomes measures in idiopathic intracranial hypertension

Expert Rev Neurother. 2021 Jun 7:1-14. doi: 10.1080/14737175.2021.1931127. Online ahead of print.ABSTRACTIntroduction: Idiopathic intracranial hypertension is a condition characterized by raised intracranial pressure, papilledema, and normal neuroimaging (aside from radiological signs of raised intracranial pressure). Symptoms of idiopathic intracranial hypertension include chronic headaches and for some, visual loss. New treatments are unmet clinical needs.Areas covered: The aim of this review is to present the evidence base and considered opinion on outcome measures to determine successful management of idiopathic intracranial hypertension.Expert opinion: Less invasive measures of disease activity such as optical coherence tomography will continue to grow in this field, both as a measure of papilledema, and potentially as a surrogate for intracranial pressure and visual function. As a highly disabling aspect of the disease is headache, treatment outcomes for headache morbidity need to be appropriately chosen and standardized to allow comparison between trials.PMID:34047224 | DOI:10.1080/14737175.2021.1931127
Source: Expert Review of Neurotherapeutics - Category: Neurology Authors: Source Type: research