CHD4 variants are associated with childhood idiopathic epilepsy with sinus arrhythmia

CONCLUSIONS: CHD4 was potentially a candidate pathogenic gene of childhood idiopathic epilepsy with arrhythmia. The molecular sub-regional effect of CHD4 mutations helped explaining the mechanisms underlying phenotypic variations.PMID:34109749 | DOI:10.1111/cns.13692

Source: CNS Neuroscience and Therapeutics - June 10, 2021 Category: Neuroscience Authors: Xiao-Rong Liu Ting-Ting Ye Wen-Jun Zhang Xuan Guo Jie Wang Shao-Ping Huang Long-Shan Xie Xing-Wang Song Wei-Wen Deng Bing-Mei Li Na He Qian-Yi Wu Min-Zhi Zhuang Meng Xu Yi-Wu Shi Tao Su Yong-Hong Yi Wei-Ping Liao China Epilepsy Gene 1.0 Project Source Type: research