Identification of Potential Genes Associated with Vemurafenib Efficacy and Melanoma Prognosis

CONCLUSION: MMP2, CXCL8, PIK3R3, ITGB3, and LEF1 may play roles in the efficacy of vemurafenib treatment in melanoma; for example, MMP2 and PIK3R3 are likely associated with vemurafenib resistance. These findings will contribute to the development of novel therapies for melanoma.PMID:34082668 | DOI:10.2174/1386207324666210603152044
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Source Type: research