Curcumin Targets Both Apoptosis and Necroptosis in Acidity-Tolerant Prostate Carcinoma Cells

CONCLUSION: This study shows that curcumin simultaneously induces apoptosis and necroptosis by oxidative mitochondrial dysfunction and subsequent ATP depletion, providing a mechanistic basis for understanding the novel role of curcumin for prostate carcinoma cells.PMID:34095313 | PMC:PMC8164543 | DOI:10.1155/2021/8859181

Source: Biomed Res - June 7, 2021 Category: Research Authors: Yoon-Jin Lee Kwan-Sik Park Sang-Han Lee Source Type: research