Prognostic importance of MRI detected extramural venous invasion in rectal cancer: a literature review and systematic meta-analysis

Extramural venous invasion (EMVI) is recognised to be a poor prognostic factor in rectal cancer. There are well documented limitations associated with pathology detection of EMVI, including variable reporting and the inability for it to be used preoperatively to guide neoadjuvant treatment. MRI detected EMVI (mrEMVI) has been proposed as an imaging biomarker. This review assesses the prognostic significance of mrEMVI on survival outcomes and whether regression of mrEMVI after neoadjuvant therapy is associated with improvements in survival.

Source: International Journal of Radiation Oncology * Biology * Physics - June 10, 2021 Category: Radiology Authors: J.J. Tan, R.V. Carten, A. Babiker, M. Abulafi, A.C. Lord, G. Brown Tags: Clinical Investigation Source Type: research