Neonatal hyperthyroidism on rat heart: interrelation with nitric oxide and sex

Conclusions The results of this study demonstrating clinically relevant sex-related differences in the pathophysiology of the hyperthyroid heart have raised new questions regarding the mechanisms responsible for the observed differences. This study suggests that sex-related intrinsic factors such as nitric oxide may modulate the response to hyperthyroidism that leads to cardiovascular dysfunction.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research