Dynamics of HIV reservoir decay and na ïve CD4 T-cell recovery between immune non-responders and complete responders on long-term antiretroviral treatment

CONCLUSIONS: INR maintained significantly higher viral reservoir and lower naïve CD4 T-cells compared with CR during 5-year ART, however, the rates of reservoir decay and naïve CD4 T-cell percentage growth within INR were not lower than that in CR over time.PMID:34102315 | DOI:10.1016/j.clim.2021.108773

Source: Clinical Immunology - June 8, 2021 Category: Allergy & Immunology Authors: Lu-Xue Zhang Jin-Wen Song Chao Zhang Xing Fan Hui-Huang Huang Ruo-Nan Xu Jia-Ye Liu Ji-Yuan Zhang Li-Feng Wang Chun-Bao Zhou Lei Jin Ming Shi Fu-Sheng Wang Yan-Mei Jiao Source Type: research