Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk

In conclusion tyrosine nitration of plasma β2GPI is demonstrated and has important implications with regards to the pathophysiology of platelet mediated thrombosis in APS. Elevated plasma levels of nβ2GPI in primary APS may be a risk factor for thrombosis warranting further investigation.PMID:34098405 | DOI:10.1016/j.jaut.2021.102675

Source: Journal of Autoimmunity - June 7, 2021 Category: Allergy & Immunology Authors: M Krilis M Qi Y Ioannou J Y Zhang Z Ahmadi J W H Wong P G Vlachoyiannopoulos H M Moutsopoulos T Koike A D Sturgess B H Chong S A Krilis B Giannakopoulos Source Type: research