Use of Negative Pressure Ventilation in Pediatric Critical Care: Experience in 56 PICUs in the Virtual Pediatric Systems Database (2009–2019)

CONCLUSIONS: Negative pressure ventilation is being used in many PICUs, most commonly for pulmonary infections or cardiac disease, in children with high rates of subsequent intubation and mortality and with few documented adverse events. Use at individual centers is rare but increasing, suggesting need for prospective collaboration to better evaluate the role of negative pressure ventilation in the PICU.
Source: Pediatric Critical Care Medicine - Category: Pediatrics Tags: Online Brief Report Source Type: research

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Bronchiolitis is the primary infection of the lower respiratory tract in children under 2 years of age. Although it is generally considered a single nosological entity, recent studies suggested remarkable clin...
Source: Italian Journal of Pediatrics - Category: Pediatrics Authors: Tags: Research Source Type: research
In Reply Dr Keim-Malpass and colleagues raise interesting points about our study of continuous pulse oximetry monitoring in bronchiolitis. First, they comment that the evidence underlying the American Academy of Pediatrics recommendation against continuous pulse oximetry is weak and that parents find physiologic monitoring reassuring; therefore, calls for deimplementation are unwarranted. This logic suggests that weak evidence of harm (without evidence of benefit) and parent preference justify implementation of a medical intervention. We disagree. Similar logic likely contributed to the overprescribing of antibiotics for m...
Source: JAMA - Category: General Medicine Source Type: research
To the Editors Dr Bonafide and colleagues found variability among hospitals in the use of pulse oximetry after discontinuation of oxygen therapy in children hospitalized for bronchiolitis. They suggested that oxygen monitoring should be deimplemented. We have 3 concerns.
Source: JAMA - Category: General Medicine Source Type: research
Abstract Intravenous fluids are frequently used in hospitalized children. Hypotonic fluids have been the standard of care in pediatrics for many years. This might be explained by the empiricism of early recommendations favoring fluids with dextrose, but an insufficient amount of sodium. The risk of hyponatremia (
Source: Archives de Pediatrie - Category: Pediatrics Authors: Tags: Arch Pediatr Source Type: research
Viral infections of the upper and lower respiratory tracts are among the most common illness in humans, mainly in children and infants in whom the infection can occur 5 to 6 times for year (Berry et al, 2015). For this reason, acute respiratory infections (ARIs) represent a persistent public health problem; although the majority of ARIs remain confined to the upper tract (rhinosinusitis, pharyngitis, laryngitis, tracheitis) they can cause severe manifestations when affecting the lower tract (bronchitis, bronchiolitis, and pneumonia) (Bicer et al., 2013; Tregoning and Schwarze, 2010; Zappa et al., 2008).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
The relationship between bronchopulmonary Pseudomonas aeruginosa and chronic lung allograft dysfunction (CLAD) has often stimulated considerations of primacy. Which came first, the chicken or the egg? Unlike binary logic, natural circumstances are more complex and demand a pluralistic view of causality, notwithstanding the recognition that in systems of coexistence, mitigation of deleterious outcomes can still be achieved by reducing one of the driving factors in the equation. So it is with airway disease, both large and small, after lung transplantation [1, 2]. Mucosal and structural damage promote an unhealthy local mili...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Editorials Source Type: research
Donor-recipient human leukocyte antigen (HLA)-DR locus matching may be protective against bronchiolitis obliterans syndrome (BOS) in lung transplant recipients. It is unknown whether this benefit is more significant among sensitized (CPRA>0%) and highly sensitized (CPRA ≥80%) recipients, who may be at higher risk for BOS.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
24 September 2020 - update to recommendations on admission to paediatric ward / HDU and revised flow chart with clarification on risk assessment and 2nd SARS-CoV-2 PCR testing
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
CONCLUSIONS: Children exposed to prenatal and postnatal maternal smoking have a higher risk of suffering bronchiolitis. Reducing the smoking habit in women that intend to become pregnant must be a priority in preventive medicine. PMID: 32988767 [PubMed - as supplied by publisher]
Source: Anales de Pediatria - Category: Pediatrics Authors: Tags: An Pediatr (Barc) Source Type: research
l CA, Kalergis AM Abstract The human respiratory syncytial virus (hRSV) is the most common infectious agent that affects children before two years of age. hRSV outbreaks cause a significant increase in hospitalizations during the winter season associated with bronchiolitis and pneumonia. Recently, neurologic alterations have been associated with hRSV infection in children, which include seizures, central apnea, and encephalopathy. Also, hRSV RNA has been detected in cerebrospinal fluids (CSF) from patients with neurological symptoms after hRSV infection. Additionally, previous studies have shown that hRSV can be d...
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
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