Use of Honey Versus Standard Care for Hospital-Acquired Pressure Injury in Critically Ill Children: A Multicenter Randomized Controlled Trial
CONCLUSIONS: The use of medicated honey dressings decreased the time to wound healing in critically ill children with pressure injuries. There were no allergic reactions or secondary bacterial infections in any of these children.
Condition: Dengue Interventions: Drug: JNJ-64281802 (sentinel high dose); Drug: JNJ-64281802 (remaining high dose); Drug: JNJ-64281802 (medium/low dose); Drug: JNJ-64281802 (dosing regimen X); Drug: JNJ-64281802 (dosing regimen Y); Drug: JNJ-64281802 (dosing regimen Z); Drug: Placebo Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); Janssen, LP; National Institutes of Health (NIH) Not yet recruiting
Conditions: Systemic Lupus Erythematosus; Cutaneous Lupus Erythematosus; SLE; CLE Interventions: Drug: tofacitinib XR; Procedure: ultraviolet light B (UVB) phototesting; Procedure: skin biopsy Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); Autoimmunity Centers of Excellence; Rho Federal Systems Division, Inc. Not yet recruiting
Conclusion: Linc00632 acted as a suppression factor in Th2 differentiation by inhibiting the expression of GATA-3 via interacting with EZH2, which might provide a new insight for understanding the action mechanism of Linc00632 in AR.Int Arch Allergy Immunol
Conclusions: Preschool children with recurrent wheezing have a greater serum periostin level than healthy control. Serum periostin may be a valuable biomarker for predicting acute wheezing exacerbations in the following year.Int Arch Allergy Immunol
The presence of sesame allergy and its importance are increasing. Objective: To determine the results of sesame and tahini oral food challenges (OFCs) and whether sesame-sIgE and skin prick tests (SPTs) accurately predicted sesame allergy in children.
For this installment of ‘From the Pages of Allergy Watch’ I've selected articles from the July-Aug issue. The first, reviewed by Dr Lee, suggests that pretreatment with H1&H2 antihistamines and montelukast can reduce the risk for reaction to COVID-19 vaccination. The next, reviewed by Dr Hernandez-Trujillo, reports data suggesting that alpha-gal allergy can be a problem even in areas not endemic for the lone star tick. The last article, reviewed by Dr Joshi, presented data suggesting that children with more severe atopic dermatitis are more likely to have learning disabilities.
CAPSULE SUMMARYThis network meta-analysis is the first to inform comparative efficacy/safety of all monoclonal antibodies and aspirin desensitization in CRSwNP showing clinically important differences in effects which inform selection of optimal therapy for patients with CRSwNP.
Increased attention towards infection control measures during the COVID-19 pandemic have brought to light the dermatological consequences of intensified hand hygiene measures. Healthcare workers are inherently at an increased risk of developing both allergic and irritant contact dermatitis. Individuals with a history of atopy are especially vulnerable given their impaired native skin barriers and increased sensitivities at baseline. Examination gloves not only induce contact allergies from manufacturing chemicals, but also serve as an occlusive catalyst for facilitating contact sensitization and irritant dermatitis. Simila...
Conclusions: Textile workers in two companies in Nam Dinh, Vietnam had a high prevalence of dust-related allergic asthma compared to estimates from the general population. There is a need to design appropriate measures of prevention, screening, and care for dust-related asthma in the textile industry. Further evaluation with better exposure assessment is necessary.
Phoenix-based Allergy Associates and Asthma Ltd. (AAA), which has multiple locations in the Valley, has teamed up with a national company to bring new treatments to its patients. The partnership will be the Arizona debut for Aspire Allergy&Sinus, which is based in Austin, Texas, and now has nearly 60 clinics in five states. The company is known for developing treatments such as allergy drops, ExACT Immunoplasty for environmental, household, and seasonal allergies, and oral immunotherapy for food …