Pertactin-Deficient B. pertussis and Pertussis Reemergence Pertactin-Deficient B. pertussis and Pertussis Reemergence

The recent reemergence of pertussis has led to an increase in pertactin-deficient strains. Are current vaccines effective against these mutations?Emerging Infectious Diseases
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

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Experts say the policy prompts people happy to vaccinate their children but doesn ’t work on those who oppose vaccination scienceAustralia ’s “no jab, no pay” policy has been associated with a drop in the number of children catching up on their first dose of the measles, mumps and rubella vaccine, suggesting the policy has had little impact on those who reject vaccination science.However, the policy was associated with more children catching up on their second dose of the vaccine and on their diphtheria –tetanus–pertussis vaccine, especially in lower socioeconomic status areas, the study...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Health Vaccines and immunisation Science Australia news Source Type: news
Abstract Vaccination of pregnant women with influenza vaccine and tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) can decrease the risk for influenza and pertussis among pregnant women and their infants. The Advisory Committee on Immunization Practices (ACIP) recommends that all women who are or might be pregnant during the influenza season receive influenza vaccine, which can be administered at any time during pregnancy (1). ACIP also recommends that women receive Tdap during each pregnancy, preferably during the early part of gestational weeks 27-36 (2,3). Despite these recommen...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
THURSDAY, Oct. 1, 2020 -- About 61 percent of pregnant women received the influenza vaccination and 56.6 percent received the reduced diphtheria toxoid and acellular pertussis (Tdap) vaccination in 2019 to 2020, according to research published in...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
THURSDAY, Oct. 1, 2020 -- About 61 percent of pregnant women received the influenza vaccination and 56.6 percent received the reduced diphtheria toxoid and acellular pertussis (Tdap) vaccination in 2019 to 2020, according to research published in...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Incidence and mortality of pertussis disease in infants
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Lack of evidence supporting a role of IFN-β and TGF-β in differential polarization of Bordetella pertussis specific-T cell responses. Cytokine. 2020 Sep 28;137:155313 Authors: da Silva Antunes R, Quiambao LG, Soldevila F, Sutherland A, Peters B, Sette A Abstract Bordetella Pertussis (BP) vaccine-induced immunity is waning worldwide despite excellent vaccine coverage. Replacement of the whole-cell inactivated vaccine (wP) by an acellular subunit vaccine (aP) is thought to play a major role and to be associated with the recurrence of whooping cough. Previously, we detected that the polarizatio...
Source: Cytokine - Category: Molecular Biology Authors: Tags: Cytokine Source Type: research
CONCLUSIONS: Linking family assistance payments with childhood vaccination status and associated program improvements were followed by substantial catch-up vaccination activity, particularly in young people from families of lower socio-economic status. PMID: 32951230 [PubMed - as supplied by publisher]
Source: Med J Aust - Category: General Medicine Authors: Tags: Med J Aust Source Type: research
Maternal influenza and pertussis vaccinations have been proven safe and effective in reducing maternal and infant morbidity and mortality. Though recommended, not all pregnant women receive these important vac...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
While the world waits for a COVID-19 vaccine, children across the globe are going without shots already known to be life-saving. With the world in disarray due to the COVID-19 pandemic, the number of children vaccinated this year against infections like diphtheria, tetanus, pertussis, measles and pneumococcal disease has fallen to levels not seen since the 1990s, according to a new report from the Bill and Melinda Gates Foundation. “In other words,” the report reads, “we’ve been set back about 25 years in about 25 weeks.” That stark figure comes from the Gates Foundation’s annual Goalkee...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Abstract Infection is the predominant cause of mortality in early life, and immunization is the most promising biomedical intervention to reduce this burden. However, very young infants fail to respond optimally to most vaccines currently in use, especially neonates. In 2005, Stanley Plotkin proposed that new delivery systems would spur a new revolution in pediatric vaccinology, just as attenuation, inactivation, cell culture of viruses, genetic engineering, and adjuvantation had done in preceding decades. Recent advances in the field of immunoengineering, which is evolving alongside vaccinology, have begun to inc...
Source: Pediatric Research - Category: Pediatrics Authors: Tags: Pediatr Res Source Type: research
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