Patients with hematologic cancers are more vulnerable to COVID-19 compared to patients with solid cancers

AbstractPrevious studies reported that COVID-19 patients with cancer had higher rates of severe events such as intensive care unit (ICU) admission, mechanical ventilation (MV) assistance, and death during the COVID-19 course compared to the general population. However, no randomized study compared the clinical course of COVID-19 in patients with hematologic cancers to patients with solid cancers. Thus, in this study, we intend to reveal the outcome of COVID-19 in hematologic cancer patients and compare their outcomes with COVID-19 patients with solid cancers. The data of 926 laboratory-confirmed COVID-19 patients, including 463 hematologic cancer patients and an age-gender paired cohort of 463 solid cancer patients, were investigated retrospectively. The frequencies of severe and critical disease, hospital and ICU admission, MV assistance were significantly higher in hematologic cancer patients compared with the solid cancer patients (p = 0.001,p = 0.045,p = 0.001, andp = 0.001, respectively). The hospital stay was longer in patients with hematologic cancers (p = 0.001); however, the median ICU stay was 6 days in both groups. The case fatality rate (CFR) was 14.9% in patients with hematologic cancers, and it was 4.8% in patients with solid cancers, and there was a statistically significant difference regarding CFR between groups (p = 0.001). Our study revealed that COVID-19 patients with ...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research

Related Links:

Conclusions: Lung CT imaging combined with clinical and laboratory findings can facilitate early diagnosis and appropriate management of COVID-19 pneumonia with a history of malignancy and radiation therapy. PMID: 33029098 [PubMed - in process]
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Molecules, Vol. 25, Pages 4597: NMR as a “Gold Standard” Method in Drug Design and Discovery Molecules doi: 10.3390/molecules25204597 Authors: Emwas Szczepski Poulson Chandra McKay Dhahri Alahmari Jaremko Lachowicz Jaremko Studying disease models at the molecular level is vital for drug development in order to improve treatment and prevent a wide range of human pathologies. Microbial infections are still a major challenge because pathogens rapidly and continually evolve developing drug resistance. Cancer cells also change genetically, and current therapeutic techniques may be...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
ConclusionsCompared to pre-COVID era, the clinical workflow was highly re-organized, whereas there were no consistent changes in RT indications and schedules.
Source: La Radiologia Medica - Category: Radiology Source Type: research
AbstractPurpose of ReviewCardiotoxicity by anticancer agents has emerged as a multifaceted issue and is expected to affect both mortality and morbidity. This review summarizes clinical challenges in the management of oncological patients requiring anticoagulants for atrial fibrillation (AF) also considering the current outbreak of the COVID-19 (coronavirus disease 2019) pandemic, since this infection can add challenges to the management of both conditions. Specifically, the aims are manyfold: (1) describe the evolving use of direct oral anticoagulants (DOACs) in AF patients with cancer; (2) critically appraise the risk of ...
Source: Current Heart Failure Reports - Category: Cardiology Source Type: research
ConclusionsDespite the introduction of strict COVID-19 control measures, there was a high level of cancer outpatient satisfaction. The satisfaction levels may influence compliance, continuity of treatments, and patient –doctor communication, impacting the quality of clinical care in the next phases of the pandemic.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
As solutions like remote care are becoming the norm, 3D-printing disrupts the normal supply chain and even the number of life science studies on tools like artificial intelligence (A.I.) skyrocket, it’s become clear that we are not anticipating the digital health era; we are in the digital health era due to the COVID-19 pandemic.  First and foremost, it’s an era defined by a cultural transformation that will upend the traditional structure of healthcare. Clinical-grade sensors are available outside of the ivory towers of medicine; patients demand such tools so that they can become more proactive in mana...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Digital Health Research E-Patients Future of Medicine Future of Pharma Genomics Health Sensors & Trackers Healthcare Design Healthcare Policy Personalized Medicine Security & Privacy Telemedicine & Smartphones amazon device epati Source Type: blogs
[Monitor] It is common knowledge that people living with non-communicable diseases (NCDs) such as hypertension, cancer, diabetes, and chronic respiratory disease, are more vulnerable to catching a severe form of Covid-19, and dying.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Background: It is widely accepted that multidisciplinary team meetings (MTM) ensure higher quality of care and improved survival in breast cancer (BC) patients. During the COVID-19 outbreak in Northern Italy, in the large territory of ULSS6 “Euganea” (province of Padova, nearly one million people and 3 local hospitals: Cittadella – CTD, Camposampiero – CSP, Schiavonia -SCH) since the end of February 2020, SCH were turned into “COVID-19 hospital” and BC cancer patients were then transferred to CTD in order to underwent surge ry.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS B: Optimal Diagnosis Source Type: research
Background: The recent COVID-19 pandemic has caused profound changes on the health-care systems as well as deleterious repercussions on the care of patients with cancer. In this comparative study, we sought to evaluate the effects the COVID-19 pandemic on the surgical management of breast cancer in a Breast Unit belonging to an Italian region with a low incidence of COVID-19 infection.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: PROFFERED PAPER SESSION: Measuring Impact of COVID-19 on Breast Cancer Care Source Type: research
In this study, we aimed to address cancer-related operations during the COVID-19 outbreak. We retrospectively reviewed 26 patients who had undergone cancer surgeries admitted from March 13 to May 13, 2020, during the COVID-19 epidemic at Istanbul Bagcilar Training and Research Hospital, as a pandemic hospital. A total of 26 cases of COVID-19 were enrolled in the study. Seventeen (65%) were female, and 9 (35%) were male. The mean age was 52.4 (range 28 –74). The mean body mass index (BMI) is 27.8 kg/m2 (range 17.6 –34.0). Eight of them had comorbidities. 7 patients needed an intensive care unit (ICU). Only ...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
More News: Cancer | Cancer & Oncology | COVID-19 | Emergency Medicine | Hematology | Hospitals | Intensive Care | Laboratory Medicine | Outbreaks | Statistics | Study