Synthetic Fibrin-Derived B β15-42 Peptide Delays Thrombus Resolution in a Mouse Model

CONCLUSIONS: Our data suggest that excess of the fibrin fragment Bβ15-42 misguides thrombus resolution, presumably by inhibiting vascular endothelial cadherin-mediated leukocyte migration during early thrombus organization.PMID:34078093 | DOI:10.1161/ATVBAHA.121.316404

Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 3, 2021 Category: Cardiology Authors: Stella Chausheva Bassam Redwan Smriti Sharma Nara Marella Klaudia Schossleitner Andr é C Mueller Peter Petzelbauer Timothy Morris Irene M Lang Source Type: research