Validity and reliability of the Neuromuscular Gross Motor Outcome

Approved treatments in spinal muscular atrophy (SMA) have resulted in unprecedented gains for many individuals. Use of available outcomes, typically developed for a specific type of SMA, do not cover the range of progression, often resulting in a battery of functional testing being completed at visits. Our objective was to validate the Neuromuscular Gross Motor Outcome (GRO) as a tool to quantify function in SMA across the span of abilities. Patients with genetically confirmed SMA completed functional testing at each visit including the Neuromuscular GRO and other appropriate gross motor outcomes.

Source: Pediatric Neurology - June 7, 2021 Category: Neurology Authors: Lindsay N. Alfano, Megan A. Iammarino, Natalie F. Reash, Brenna R. Powers, Kiana Shannon, Anne M. Connolly, Megan A. Waldrop, Garey H. Noritz, Richard Shell, Chang-Yong Tsao, Kevin M. Flanigan, Jerry R. Mendell, Linda P. Lowes Tags: Research Paper Source Type: research