Tumefactive multiple sclerosis versus high-grade glioma: A diagnostic dilemma

CONCLUSION: The diagnostic pathway, proposed on the basis of specific clinicoradiological features, should be followed in patients with suspected TDL. If MRI demonstrates other lesions typical of MS and LP demonstrates positive CSF-specific OCBs, then patients should undergo a short course of IV steroids to look for clinical improvement. Patients who continue to deteriorate, do not demonstrate other lesions on MRI or where the LP is negative for CSF-specific OCB, should be considered for biopsy if safe to do so. This pathway will give the patients the best chance at neurological preservation.PMID:34084626 | PMC:PMC8168700 | DOI:10.25259/SNI_901_2020
Source: Surgical Neurology International - Category: Neurosurgery Authors: Source Type: research