FOXL2 and TERT promoter mutation detection in circulating tumor DNA of adult granulosa cell tumors as biomarker for disease monitoring
CONCLUSIONS: FOXL2 mutant ctDNA was present in the majority of aGCT patients and TERT promoter mutant ctDNA has been identified in a smaller subset of patients. Both FOXL2 and TERT mutant ctDNA detection may have clinical value in disease monitoring.PMID:34083028 | DOI:10.1016/j.ygyno.2021.05.027
Source: Gynecologic Oncology - Category: Cancer & Oncology Authors: Jolijn W Groeneweg Joline F Roze Edith D J Peters Ferdinando Sereno Anna G J Brink Sterre T Paijens Hans W Nijman Hannah S van Meurs Luc R C W van Lonkhuijzen Jurgen M J Piek Christianne A R Lok Glen R Monroe Gijs W van Haaften Ronald P Zweemer Source Type: research
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