Metoprolol attenuates intracerebral hemorrhage-induced cardiac damage by suppression of sympathetic overactivity in mice

In this study, we investigated the role of sympathetic overactivity in mediating cardiac dysfunction post ICH in mice. Collagenase-injection ICH model was established in adult male C57BL/6J mice. Neurological function was subsequently evaluated at multiple time points after ICH and cardiac function was measured by echocardiography on 3 and 14  days after ICH.

Source: Autonomic Neuroscience: Basic and Clinical - June 5, 2021 Category: Neuroscience Authors: Liqun Zhang, Jimusi Wuri, Lulu An, Xiaoxuan Liu, Ye Wu, Haotian Hu, Ruixia Wu, Yue Su, Quan Yuan, Tao Yan Source Type: research