Aging and CNS myeloid cell depletion attenuate breast cancer brain metastasis

CONCLUSIONS: Host microenvironmental factors contribute to the aggressiveness of triple-negative and luminal B breast cancer brain metastasis. CSF-1R inhibitors may hold promise for young brain metastasis patients.PMID:34083229 | DOI:10.1158/1078-0432.CCR-21-1549

Source: Clinical Genitourinary Cancer - June 4, 2021 Category: Cancer & Oncology Authors: Alex Man Lai Wu Selamawit Gossa Ramakrishna Samala Monika A Chung Brunilde Gril Howard Yang Helen R Thorsheim Andy D Tran Debbie Wei Esra Taner Kristine Isanogle Yuan Yang Emma L Dolan Christina M Robinson Simone Difilippantonio Maxwell Lee Imran Khan Que Source Type: research