Prevalence, healthcare resource utilization and mortality of Lennox-Gastaut syndrome: retrospective linkage cohort study

Lennox-Gastaut syndrome (LGS) is a rare childhood-onset epileptic encephalopathy (1 –10% of childhood epilepsy cases depending on age),1 typically diagnosed in children under 8 years of age.2 It is one of the most severe and difficult epileptic disorders to identify and manage2,3 because of its highly variable presentation1–3 and evolving features over time.2,3 In addition, a n umber of seizure types may present at the onset of LGS,2 often resistant to treatment,2 resulting in variable outcomes following treatment.

Source: Seizure: European Journal of Epilepsy - June 4, 2021 Category: Neurology Authors: Richard F.M. Chin, W. Owen Pickrell, Florent Guelfucci, Monique Martin, Rowena Holland Source Type: research