Diagnostic and therapeutic challenge of unclassifiable enteropathies with increased intraepithelial CD103 < sup > + < /sup > CD8 < sup > + < /sup > T lymphocytes: a single center case series

CONCLUSIONS: We report a patient population with 'difficult-to-classify' enteropathies characterized by various degrees of villous atrophy and strongly increased intraepithelial CD103+ CD8+ T cells in the small intestine which harbor an increased risk for T-cell lymphoproliferative disorders. Clinical course, histology, and response to immunosuppressive therapy all suggest an autoimmune pathogenesis.PMID:34057863 | DOI:10.1080/00365521.2021.1931958
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research