The International Family Study of Nonsyndromic Orofacial Clefts: Design and Methods

DISCUSSION: The International Family Study is the largest case set of NSOFCs with an associated biobank in LMICs currently assembled. The biobank, family, and case-control study now include samples from 8 LMICs where local health care infrastructure cannot address the surgical burden of cleft or investigate causal mechanisms. The International Family Study can be a source of information and may collaborate with local public health institutions regarding education and interventions to potentially prevent NSOFCs.PMID:34056937 | DOI:10.1177/10556656211018956
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Source Type: research