The neurobiological effects of electroconvulsive therapy studied through magnetic resonance – what have we learnt and where do we go?

Electroconvulsive Therapy (ECT) is an established treatment choice for severe, treatment-resistant depression, yet its mechanisms of action remain elusive. Magnetic resonance imaging (MRI) of the human brain before and after treatment, has been crucial to aid our comprehension of the ECT neurobiological effects. However, to date the majority of MRI studies have been underpowered, used heterogeneous patient samples as well as different methodological approaches, altogether causing mixed results and poor clinical translation.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Review Source Type: research