Finding New Optimism In Those Pandemic Babies

Well hello! I’m so glad you’re here. A version of this article also appeared in theIt’s Not Just You newsletter.Sign up here to receive a new edition every Sunday. As always, you can send comments to me at: A slew of beloved friends have been having babies lately. I’m embarrassingly emotional about their arrival, or even just the news that they’re on their way. Knowing that this new crop of young ones will uncover delight in this bruised world is one of those ancient wonders. [time-brightcove not-tgx=”true”] It’s been a fractious and scary year, but these pandemic babies will still laugh deliriously at the smallest of forgotten joys, like squeezing mashed potatoes through their fingers or grabbing the dog’s nose. And in turn, that’ll make the adults who love them lose themselves to joy. It’s an ordinary but precious intergenerational symphony: We believe our job is to teach kids everything, meanwhile, they’re reminding us how to live. I like thinking that this newest generation will be an especially bright light, maybe because their existence is such a stubbornly optimistic bet on the future in the face of what economists predict will be a drop in birth rates for 2021. This delay in parenthood is the price of economic hardship, a pandemic, and political agonies across the globe. Surely this baby bust will wane as we emerge into the light of what we hope will be a summer of optimism. How...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized It's Not Just You Source Type: news

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Conclusions: Tac IPV6–24 was higher and more significantly associated with DSA development and/or late rejection than Tac IPV6–12, independent of Tac trough level. This is the first study to demonstrate the impact of high IPV on DSA development in Asian patients, and that Tac IPV is comparable between patients with and without CYPinh.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Original Article Source Type: research
Conclusions: The consistency of the new FICA using a point-of-care testing device with LC-MS/MS and EMIT was inadequate, and the accuracy of EMIT and LC-MS/MS was inappropriate. Clinicians should be informed when switching MPA detection methods to avoid misleading results.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Original Article Source Type: research
Conclusions: Similar to nontransplant patients, KT patients administered the standard 5-mg bid dosage had apixaban levels that were well within the recommended manufacturers' expected ranges. In addition, this dosage had minimal influence on immunosuppression and no effect on graft function.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Original Article Source Type: research
Conclusions: A proficiency testing program by which laboratories are alerted to inaccuracies in their quantitation, pharmacokinetic modeling, and dose recommendations for busulfan in hematopoietic cell transplant recipients was developed. These rounds of proficiency testing suggests that additional educational efforts and proficiency rounds are needed to ensure appropriate busulfan dosing.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Original Manuscript Source Type: research
Conclusions: Intravenous infusion of fentanyl does not affect the pharmacokinetics of TAC.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Short Communication Source Type: research
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social behaviors and communication. In rodents and humans, prenatal exposure to antiepileptic valproic acid is associated with an increased risk for autistic-like characteristics. One potential treatment is oxytocin, a prosocial neuropeptide that can be delivered intranasally. However, the sex-specific effects of valproic acid exposure and intranasal oxytocin treatment on behavior have not been fully explored. Pregnant Long Evans rats were administered valproic acid (500 mg/kg) or saline midday on gestational day 12, ...
Source: Behavioural Pharmacology - Category: Drugs & Pharmacology Tags: Research Reports Source Type: research
We report evaluation of 30 assays ’ (17 rapid tests (RDTs) and 13 automated/manual ELISA/CLIA assay (IAs)) clinical performances with 2594 sera collected from symptomatic patients with positive SARS-CoV-2 rRT-PCR on a respiratory sample, and 1996 pre-epidemic serum samples expected to be negative. Only 4 RDT and 3 IAs fitted both specificity (> 98%) and sensitivity (> 90%) criteria according to French recommendations. Serology may offer valuable information during COVID-19 pandemic, but inconsistent performances observed among the 30 commercial assays evaluated, which underlines the importance of independent ev...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
The objective of this study is to explore whether ambient temperature is associated with increased risk of EPT birth.MethodsBirth records for 315,226 infants born in Queensland Australia (2007 –2015) were matched to average maximum and minimum temperature for the last month of pregnancy. Odds ratios and 95% confidence intervals were calculated using a generalised linear model. Population attributable risk was calculated for a 5% reduction in maximum temperature.ResultsEach one degree increase in maximum [aOR 1.03 (95% CI 1.01, 1.05)] and minimum temperature [aOR 1.02 (95% CI 1.01, 1.04)] was associated with an increa...
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
AbstractBackgroundAntenatal care (ANC), delivery by skilled birth attendants, and postnatal care (PNC) are critical components of maternal health services for reducing maternal mortality. The study aimed to compare the utilization of maternal health services in the two most recent rounds of Ethiopia Demographic and Health Surveys (EDHS) and identify the factors influencing the utilization of these services using the 2016 EDHS.MethodsTwo rounds of EDHS data in 2011 and 2016 were used to estimate the proportion of women who had ANC, delivered by skilled birth attendants, and had a postnatal checkup and other characteristics ...
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
ConclusionThe ability to incentivize innovation to address critical public health issues cannot rest in the private sector alone. Complementing other investments, the Challenge mechanism ’s power to catalyze the rapid development of innovative solutions can improve how we address barriers to achieve optimal maternal and child health for the families that we serve.
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
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