HEPATIC stellate cell-derived exosomes MODULATE macrophage inflammatory response

CONCLUSIONS: HSC-EXOs associate with macrophages and stimulate cytokine synthesis-release and macrophage migration. Constructing a comprehensive understanding of EXOs interactions between liver cell populations in the setting of inflammation/fibrosis increases the potential for developing new diagnostic/therapeutic approaches.PMID:34051242 | DOI:10.1016/j.yexcr.2021.112663

Source: Experimental Cell Research - May 29, 2021 Category: Cytology Authors: Jennifer H Benbow Emilio Marrero Rachel M McGee Elizabeth Brandon-Warner Neha Attal Nicole A Feilen Catherine R Culberson Iain H McKillop Laura W Schrum Source Type: research