Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice

CONCLUSION: Naltrexone reduced TBI-mediated neurodegeneration and inflammation in MOR WT and KO mice. The protective effect of naltrexone involves non-MOR and MOR mechanisms.PMID:34018697 | DOI:10.1111/cns.13655

Source: CNS Neuroscience and Therapeutics - May 21, 2021 Category: Neuroscience Authors: Yu-Syuan Wang Tsai-Wei Hung Eun-Kyung Bae Kuo-Jen Wu Wei Hsieh Seong-Jin Yu Source Type: research