Dynamics of serum α-fetoprotein in viral hepatitis C without hepatocellular carcinoma

In conclusion, the data revealed that a moderate increase in AFP levels could be present in patients with HCV even in the absence of HCC, unrelated to viral load or therapy response and that there was a linear positive correlation between serum levels of AFP and the degree of hepatic cytolysis and cholestasis. Additionally, mixed cryoglobulinemia was present in HCV patients with patent viral load, decreasing in those with SVR after therapy cessation unrelated to any renal impairment, while the degree of fibrosis was increased in HCV-infected patients, with no reversibility 12 weeks after successful therapy.PMID:34035846 | PMC:PMC8135122 | DOI:10.3892/etm.2021.10181
Source: Experimental and Therapeutic Medicine - Category: General Medicine Authors: Source Type: research