Absence of interferon- λ 4 enhances spontaneous clearance of acute hepatitis C virus genotypes 1-3 infection

CONCLUSIONS: Absence of IFN-λ4 entails an enhanced likelihood of spontaneous resolution both following primary acute infection and repeated re-exposure to HCV across genotypes 1-3. Among men lacking IFN-λ4, reduced ITPase activity improved outcome.PMID:34034600 | DOI:10.1080/00365521.2021.1925956

Source: Scandinavian Journal of Gastroenterology - May 26, 2021 Category: Gastroenterology Authors: Jesper Waldenstr öm Martin K åberg Marianne Alanko Blom é Anders Widell Per Bj örkman Staffan Nilsson Anders Hammarberg Ola Weiland Kristina Nystr öm Martin Lagging Source Type: research