Inhibition of Maternal-to-Fetal Transfer of IgG Antibodies by FcRn Blockade in a Mouse Model of Arthrogryposis Multiplex Congenita

Conclusions
FcRn blockade is a promising therapeutic strategy to prevent the occurrence of AMC and other human maternal autoantibody-related diseases in the offspring.

Source: Neurology Neuroimmunology and Neuroinflammation - May 27, 2021 Category: Neurology Authors: Coutinho, E., Jacobson, L., Shock, A., Smith, B., Vernon, A., Vincent, A. Tags: Autoimmune diseases, Myasthenia, Developmental disorders Article Source Type: research