Klotho protects against diabetic kidney disease via AMPK- and ERK-mediated autophagy

ConclusionIn summary, our results proved that Klotho improved renal tubular cell autophagy via the AMPK and ERK pathways and played a role in renal protection. These findings provide new insight into the mechanism of Klotho and autophagy in DKD.
Source: Acta Diabetologica - Category: Endocrinology Source Type: research