Higher ovulation rate with letrozole as compared with clomiphene citrate in infertile women with polycystic ovary syndrome: a systematic review and meta-analysis

CONCLUSION: A higher probability of ovulation is expected in infertile patients with PCOS treated with letrozole as compared to CC. The higher ovulation rate might have contributed to the higher clinical pregnancy and live birth rate. This finding is also true for patients who were administered letrozole as first-line treatment.TRIAL REGISTRATION: CRD42019125166.PMID:34033068 | DOI:10.1007/s42000-021-00289-z

Source: Hormones - May 25, 2021 Category: Endocrinology Authors: Alexandra P Tsiami Dimitrios G Goulis Alexandros I Sotiriadis Efstratios M Kolibianakis Source Type: research