Learn about the impact of diet on diabetes, cancer and heart disease
The Nutrition Society’s next scientific conference on 25-26 March in Aberdeen, Scotland, will focus on Diet, Gene Regulation and Metabolic Disease, and brings together leading scientific speakers on these topics from around the world: Professor Donald B Jump, Nutrition Program, School of Biological and Population Health Sciences, Oregon State University, USA; Professor Romano Regazzi, Vice-Director of the School of Medicine, Department of Fundamental Neurosciences, University of Lausanne, Switzerland; Professor Loranne Agius, Professor of Metabolic Biochemistry, Institute of Cellular Medicine, Newcastle University, The Medical School, Newcastle upon Tyne, UK; Josep C Jimenez-Chillaron, Group Leader at Paediatric Hospital Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona, Spain; Professor Mark Hanson, founding Director of the Institute of Developmental Sciences at the University of Southampton, Director of the Academic Unit of Human Development and Health in the University’s Faculty of Medicine and British Heart Foundation Professor of Cardiovascular Science, UK; Noa Noy, Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland, Ohio, USA; Dr Carles Cantó, Nestle Institute of Health Sciences, Lausanne, Switzerland; Professor Guy Rutter, Chair in Cell Biology and Head of Cell Biology, Faculty of Medicine, Imperial College London, UK Professor John Mathers, Professor of Human Nutrition, Di...
Authors: Watahiki T, Okada K, Warabi E, Nagaoka T, Suzuki H, Ishige K, Yanagawa T, Takahashi S, Mizokami Y, Tokushige K, Ariizumi SI, Yamamoto M, Shoda J Abstract Gender and menopause influence the severity and development manner of nonalcoholic steatohepatitis (NASH). Male p62/Sqstm1 and nuclear factor E2-related factor-2 (p62 and Nrf2) double-knockout (DKO) mice exhibit severe steatohepatitis caused by hyperphagia-induced obesity, overload of lipopolysaccharide (LPS) into the liver, and potentiation of the inflammatory response in Kupffer cells. However, the pathogenetic phenotype of steatohepatitis in female DKO...
Publication date: Available online 3 June 2020Source: Life SciencesAuthor(s): Wahid Ali Khan, Arshi Malik, Mohd. Wajid Ali Khan
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