Accurate evaluation of CRISPR genome editing

(Bar-Ilan University) A multidisciplinary team of researchers from the Interdisciplinary Center Herzliya and Bar-Ilan University report in the May 24th issue of the journal Nature Communications the development of a new software tool to detect, evaluate and quantify off-target editing activity, including adverse translocation events that can cause cancer. The software is based on input taken from a standard measurement assay, involving multiplexed PCR amplification and Next-Generation Sequencing (NGS).
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news