Propensity Adjusted Analysis of Open and Endovascular Thoracic Aortic Repair for Chronic Type B Dissection: A Twenty-Year Evaluation

Conclusions Intervention for CBAD can be performed with excellent results, either by an open or endovascular approach. The higher rate of treatment failure after TEVAR warrants modification of current device design or endovascular approach before broad application of this treatment strategy.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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CONCLUSIONS: No differences were seen between the sexes in life-changing adverse outcomes after ascending aortic and arch procedures, although specific preoperative variables were associated with specific adverse events. Recognizing differences in preoperative risk factors for mortality between the sexes may facilitate targeted preoperative assessment, preparation, and counseling.PMID:33971171 | DOI:10.1016/j.athoracsur.2021.04.069
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
AbstractPurpose of ReviewTo provide a highlight of the current state of cell therapy for the treatment of critical limb ischemia in patients with diabetes.Recent FindingsThe global incidence of diabetes is constantly growing with consequent challenges for healthcare systems worldwide. In the UK only, NHS costs attributed to diabetic complications, such as peripheral vascular disease, amputation, blindness, renal failure, and stroke, average £10 billion each year, with cost pressure being estimated to get worse. Although giant leaps forward have been registered in the scope of early diagnosis and optimal glycaemic con...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
 Written by Pendell MeyersA 59-year-old woman with diabetes, hypertension, prior stroke, and peripheral vascular disease presented with multiple near-syncopal events over the past 2 days, as well as ongoing back pain. EMS found her bradycardic in the 40s and administered atropine with no response. She was mentating and had a reasonable blood pressure (around 90s systolic), so they decided not to pace prehospital. On arrival the patients blood pressure was 79/50 mm Hg. She was still awake and alert. Here is her first ECG (no baseline available):What do you think?Findings: - junctional bradycardia (no P waves,...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
More than 4.7 million residents in the UK are estimated to have diabetes, and this number is expected to grow [1]. Type 2 diabetes, which contributes 90% of all cases of diabetes mellitus [2] is now mostly managed in the primary care settings in the UK and other advanced health care systems [3]. The huge economic burden of diabetes is driven mostly by the increased risk for macro vascular (stroke, heart disease, peripheral vascular disease,) and microvascular complications (retinopathy, and renal failure) [4], which are usually managed in specialist centres.
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Brief report Source Type: research
CONCLUSION: ICHRON predicted ChrD diagnosis at 3-years among an external, geographically distant validation cohort. These findings show the value of ICHRON for primary care patients in distinct locales. Additionally, electronic calculation of ICHRON empowers the clinical use of this tool to identify and differentially manage and treat high-risk patients. PMID: 32563688 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Eur J Intern Med Source Type: research
Conclusion: The results of the study concluded that periodontal disease and poor oral hygiene were more severe among the subjects with CIMT> 1 mm. To halt the progression of increasing CIMT, preventive oral health programmes need to be integrated in the cardiac setting with established dental referral which can bring out positive health behaviours.
Source: Oral health and Preventive dentistry - Category: Dentistry Source Type: research
CONCLUSIONS: This study provides novel information regarding the probability of uneventful recovery while confirming low in-hospital mortality and stroke rates after elective aortic root replacement for aortic aneurysm. Importantly, uneventful recovery ensures excellent long-term survival. PMID: 32246934 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
AbstractPurposeTo investigate risk factors for severe bleeding during warfarin treatment, including the influence of sex, age, comorbidity and co-medication on bleeding risk.MethodsPatients initiating warfarin treatment between 2007 and 2011 were identified in the nationwide Swedish Prescribed Drug Register, and diagnoses of severe bleeding were retrieved from the National Patient Register. Hazard ratios (HR) with 95% confidence intervals (CI) for severe bleeding were estimated using multiple Cox regression adjusting for indications and including covariates age, sex, comorbidities and co-medications. Interactions between s...
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research
Diabetes mellitus (DM) is a globally chronic condition that currently affects over 422 million people worldwide, a number that has been estimated to grow to 552 million by 2030 [1,2]. Saudi Arabia is one of the nations with the highest DM prevalence regionally and internationally [3]. Hypertension (HT) is more common in patients with diabetes than in those without diabetes [4,5]. The co-occurrence of HT has a substantial clinical effect of producing a poor outcome for patients with diabetes. Complications such as renal failure, stroke, heart disease, peripheral vascular disease, and mortality are the most adverse outcomes ...
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
CONCLUSION: Multiple complications after surgery for lower limb PAD carried a compounding risk of reduced long term amputation free survival. Patients experiencing at least one complication form a high risk group that requires increased attention to prevent the potential development of further complications. PMID: 31879146 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
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