Simultaneous Quantification of BCR-ABL and Bruton Tyrosine Kinase Inhibitors in Dried Plasma Spots and Its Application to Clinical Sample Analysis

Conclusions: An LC-MS/MS method for the simultaneous quantification of 6 TKIs in DPS was developed and validated. Further large-scale studies should be conducted to assess the consistency of concentration measurements obtained from plasma and DPS.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Focus Series: Alternative Sampling Strategies Source Type: research