Acute Effects of Ketamine Infusion on Postoperative Mood Scores in Patients Undergoing Dilation and Curettage: A Randomized Double-Blind Controlled Study

CONCLUSION: Observed data here support an acute effect of ketamine on mood but any further claim will be speculative. Further future studies exploring postoperative mood scores after 24 hours post-infusion are needed. This trial is registered with PACTR201907779292947.PMID:33859685 | PMC:PMC8009713 | DOI:10.1155/2021/6674658
Source: Anesthesiology Research and Practice - Category: Anesthesiology Authors: Source Type: research

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The prevalence of heart failure (HF) continues to increase, and its economic effect is significant in the United States and globally. During the past 2 years, a number of high-quality clinical trials were published with the aim of addressing different stages of the disease process and improving outcomes for patients with preserved and depressed ejection fraction (EF). In this review, data from these trials are summarized and critically appraised. There are several important findings from these studies, including, but not limited to, the benefit of dapagliflozin in HF with reduced EF, sacubitril-valsartan in acute decompens...
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Expert Review Source Type: research
In older adults, interactions with meds for depression, anxiety increase risk for ED visits, hospitalizations
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Family Medicine, Geriatrics, Internal Medicine, Emergency Medicine, Pharmacy, Psychiatry, Anesthesiology & amp; Pain, Journal, Source Type: news
DISCUSSION: These findings suggest that the relationship between parent factors and long-term postoperative pain outcomes may be dependent on the child's symptom profile at baseline. Since there may be bidirectional relationships between parent and child factors, interventions to mitigate long-term pain should address child symptoms as well as parental factors. PMID: 33010105 [PubMed - as supplied by publisher]
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Tags: Paediatr Anaesth Source Type: research
Hello Pain Medicine Docs, I am a CA1 at a great anesthesiology program who is really struggling with my life choices. Obviously depression is multi factorial, and it's hard to parse how much is a dislike of anesthesiology vs. a dislike of being a resident in general, but I am concerned that I made a real mistake with my specialty choice. From the outside I am doing well, I receive great evals, I am probably in the upper half of my class in terms of progression and knowledge, but I simply do... Struggling Anesthesiology Resident
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
A 5-year-old-boy (weight, 17.4 kg; height, 120 cm; body surface area, 1.02m2) with pulmonary atresia, intact ventricular septum, bipartite hypoplastic right ventricle and tricuspid valve hypoplasia presented to the author's institution for pre-Fontan evaluation. The child had under gone a bi-directional Glenn procedure at one-year of age. The electrocardiogram showed a sinus rhythm, left axis deviation, and ‘ST’ depression in V1-V3 leads. The origin of the left main coronary artery was dilated in a parasternal short axis view of the aorta by transthoracic echocardiography as well as in mid-esophageal aortic sho...
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Diagnostic Dilemma Source Type: research
Conclusion: Postoperative TEA is an advanced technique that poses certain difficulties that can subvert its great potential. While serious complications were rare, minor complications occurred more often and affected the postoperative course negatively. A risk/benefit evaluation of each patient should be done before employing the technique. PMID: 32982397 [PubMed]
Source: Local and Regional Anesthesia - Category: Anesthesiology Tags: Local Reg Anesth Source Type: research
Abstract The balance of excitatory and inhibitory neurons in the central nervous system is critical for maintaining brain function and sevoflurane, a general anesthetic and an GABA receptor modulator, may change the balance of excitatory and inhibitory neurons in the cortex during early brain development. Herein, we investigated whether prenatal sevoflurane exposure (PSE) disturbs cortical neuronal development and brain function. Pregnant rats at the gestational day 14.5 were subjected to sevoflurane exposure at 3.0% for 3 h and their offspring were studied thereafter. We found a significant increase of parvalbu...
Source: Neurobiology of Disease - Category: Neurology Authors: Tags: Neurobiol Dis Source Type: research
Condition:   Pregnancy Related Interventions:   Other: Grup I= General anesthesia group;   Other: Grup II= Spinal anesthesia group Sponsor:   Medipol University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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