A bodyguard for your ears: Scientists discover novel pain sensors in inner ear that warn of dangerously loud noise

Our hearing has a secret bodyguard, a newly discovered connection from the cochlea to the brain that warns of intense incoming noise that causes tissue damage and hearing loss. Scientists believe it's the ear's novel pain system designed to protect it from dangerous noise. Because the ear doesn't have the nerve cells that normally detect pain, it needs its own alert system. The findings could usher new treatments for painful hearing conditions like tinnitus and hyperacusis.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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CONCLUSION: There is low-quality evidence for a positive effect of conservative temporomandibular disorders treatment on tinnitus complaints. The combination of splint therapy and exercise treatment is currently the best investigated treatment approach, showing a decrease in tinnitus severity and intensity. Despite the low level of evidence and the methodologic issues in the included studies, it is noteworthy that all included studies show positive treatment effects. PMID: 30978269 [PubMed - as supplied by publisher]
Source: Journal of Orofacial Pain - Category: ENT & OMF Tags: J Oral Facial Pain Headache Source Type: research
Publication date: Available online 5 April 2019Source: NeuroImageAuthor(s): Matthew S. Sherwood, Jason G. Parker, Emily E. Diller, Subhashini Ganapathy, Kevin B. Bennett, Carlos R. Esquivel, Jeremy T. NelsonAbstractIn this work, we investigated the use of real-time functional magnetic resonance imaging (fMRI) with neurofeedback training (NFT) to teach volitional down-regulation of the auditory cortex (AC) using directed attention strategies as there is a growing interest in the application of fMRI-NFT to treat neurologic disorders. Healthy participants were separated into two groups: the experimental group received real fe...
Source: NeuroImage - Category: Neuroscience Source Type: research
‚ÄčA 50-year-old man presented to the emergency department complaining of ringing in his ears and difficulty understanding what people were saying. He was concerned that he was having a stroke. A full neurological exam was unremarkable aside from decreased hearing, but his hearing deficits appeared to be equal bilaterally. Otoscopic exam demonstrated a normal tympanic membrane, and the rest of his physical exam was unremarkable. The patient's past medical history was significant for hypertension and hypercholesterolemia, for which he took lisinopril and atorvastatin. He was recently treated with a 10-day course of doxycycl...
Source: The Tox Cave - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Atypical facial neuralgias are a rare condition, that present predominantly in the female population, with an annual incidence of 3-4 cases every 100 000 people. The trigeminal nerve root is mostly affected, and not commonly combined with autonomic symptoms. We are presenting a 59 years old, female patient, with significant medical history for anxiety, depression and autoimmune liver disease, on long term steroid treatment. She suddenly started complaining of severe periodic right facial pain about 15 years ago, after an sneezing episode, described as stabbing in quality and triggered by minor stimulus; also accompanied wi...
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
AbstractPurposeTo determine the analgesic efficacy and analgesic duration of lidocaine 20  mg and 40 mg on eliminating the vascular pain associated with hypertonic saline infusion.MethodPatients who complained pain during infusion of hypertonic saline were randomized into three groups. They received normal saline (Group C), or lidocaine 20  mg (Group L20), or lidocaine 40 mg (Group L40). An electronic stopwatch was used to record the time to onset (T1) and the time to termination (T2) of the analgesic effect, and the analgesic duration (AD) was calculated asT2  − T1.ResultsThe incide...
Source: Journal of Anesthesia - Category: Anesthesiology Source Type: research
Conclusion Cystic VS presents some unique challenges compared with their solid counterparts. The cystic tumor capsule may be very adherent to the adjacent structures, and distinguishing thin cyst walls from the arachnoid of the CPA, can be quite challenging. The retrosigmoid approach provides adequate surgical exposure for VS tumor resection.The link to the video can be found at: https://youtu.be/sFNvRWG465Q. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Journal of Neurological Surgery Part B: Skull Base - Category: Neurosurgery Authors: Tags: Skull Base: Operative Videos Source Type: research
ConclusionTinnitus was associated with deterioration of hearing even when it occurred in the better-hearing side. Among the possible etiologies, fluctuating hearing loss in the tinnitus side was the most common audiologic finding. Assessment of hearing level at each frequency was more effective in detecting high-frequency hearing loss rather than the use of the mean hearing level. In addition, somatosensory tinnitus should not be ignored.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Authors: Crincoli V, Anelli MG, Quercia E, Piancino MG, Di Comite M Abstract Aims: Temporomandibular disorders (TMD) represent a heterogeneous group of inflammatory or degenerative diseases of the stomatognatic system, with algic and/or dysfunctional clinical features involving temporomandibular joint (TMJ) and related masticatory muscles. Rheumatoid Arthritis (RA) is an autoimmune polyarthritis characterized by the chronic inflammation of synovial joints and oral implications such as hyposalivation, difficulty in swallowing and phoning, feeling of burning mouth, increased thirst, loss of taste or unpleasant taste ...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Fibromuscular dysplasia is a noninflammatory, nonatherosclerotic disease that results in fibrous tissue buildup of the medium-sized arteries. Areas of stenosis and dilation in the arteries can result in dissection or aneurysm. The stenotic areas of the vessel alternating with dilation result in what is often described as a “string of beads” appearance on imaging. Symptoms depend on location and severity of the disease. Common symptoms include migraine-type headache, flank pain, and pulsatile tinnitus.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Feature Article Source Type: research
We report a case of the concurrence of VKHD and sarcoidosis, which may share a common pathophysiology. Accumulation of further similar cases is necessary to elucidate the precise mechanism underlying the concurrence of these two diseases.Case Rep Ophthalmol 2019;10:32 –40
Source: Case Reports in Ophthalmology - Category: Opthalmology Source Type: research
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