Molecular Peritoneal Staging for Pancreatic Ductal Adenocarcinoma Using Mutant KRAS Droplet-Digital Polymerase Chain Reaction: Results of a Prospective Clinical Trial

This prospective clinical study demonstrates the feasibility of mutant KRAS DNA detection in the peritoneal lavage fluid of patients undergoing staging laparoscopy for pancreatic ductal adenocarcinoma using droplet digital polymerase chain reaction, which produces quantifiable results. Presence of mutant KRAS was associated with clinically positive laparoscopy.

Source: Journal of the American College of Surgeons - May 19, 2021 Category: Surgery Authors: Jennifer A. Yonkus, Roberto Alva-Ruiz, Amro M. Abdelrahman, Jennifer L. Leiting, Amber R. Schneider, Travis E. Grotz, Sean P. Cleary, Rory L. Smoot, David M. Nagorney, Michael L. Kendrick, Benjamin R. Kipp, Mark J. Truty Tags: Western Surgical Association Article Source Type: research