Internet-Delivered CBT Reduces Atopic Dermatitis Symptoms

WEDNESDAY, May 19, 2021 -- Internet-delivered cognitive behavior therapy (CBT) reduces symptoms of atopic dermatitis, according to a study published online May 19 in JAMA Dermatology. Erik Hedman-Lagerlöf, Ph.D., from the Karolinska Institutet...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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This week's roundup on the region's life sciences industry includes one company securing two FDA approvals, a South Jersey institution receiving a $12 million research grant, and more. Here's the rundown: Incyte Corp. The Wilmington biotechnology company started the week receiving marketing clearance from the Food and Drug Administration for Opzelura, the company's topical cream for mild-to-moderate atopic dermatitis — a chronic skin disease that affects more than 21 million people in the Unit ed…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
ConclusionsThere are clear differences in the skin microbiome of healthy controls and AD patients that diminish with treatment. After three months, the addition of DBB to standard treatment had significantly decreased the S. aureus burden, supporting its use as a therapeutic option. Further study in double-blinded trials is needed.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
In this study, we investigated the function of TRPC3, a canonical TRP channel highly expressed in type 1 non-peptidergic (NP1) nociceptive primary afferents and other cell types, in a mouse CD model. Though TrpC3 null mice had little deficits in acute somatosensation, they showed significantly increased scratching with CD. In addition, TrpC3 null mice displayed no differences in mechanic and thermal hypersensitivity in an inflammatory pain model, suggesting that this channel preferentially functions to antagonize CD-induced itch.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
AbstractThe impact of search strategies on systematic reviews (SR) of atopic dermatitis (AD) is unknown. The purpose of this review was  to evaluate search strategies used in SR of AD and their impact on the frequency of manuscripts identified. MEDLINE and EMBASE were searched for SR related to AD. Simulations were performed by running combinations of search terms in MEDLINE and EMBASE. Overall, 250 SR met inclusion criteria, of wh ich 225 specified search strategies. SR using 5–6 terms (20.0% to 12.1%) or ≥ 7 (40.0% to 18.8%) terms decreased, whereas SR using 3–4 terms numerically increas...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
AbstractThe optimal frequency of water bathing/showering in atopic dermatitis (AD) is unknown. We sought to determine the efficacy of different bathing/showering frequencies at improving AD severity. A systematic review and meta-analysis was performed of studies evaluating the clinical efficacy of bathing/showering regimen in AD. MEDLINE, EMBASE, SCOPUS, LILACS, Cochrane, China National Knowledge Infrastructure, Taiwan electronic periodical services and CiNii were searched. Two authors independently performed title/abstract and full-text review and data extraction. All 13 included studies were prospective and demonstrated ...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
CONCLUSIONS The knowledge and behavior of ICU nurses regarding IAD need to be improved. Training and management are imperative. Facilities and nurse managers should actively seek solutions to stated obstacles, formulate training methods suitable for clinical needs, and promote the standardization of nursing for IAD.
Source: Advances in Skin and Wound Care - Category: Dermatology Tags: ORIGINAL INVESTIGATIONS Source Type: research
J Med Microbiol. 2021 Sep;70(9). doi: 10.1099/jmm.0.001421.ABSTRACTThe pH of skin is critical for skin health and resilience and plays a key role in controlling the skin microbiome. It has been well reported that under dysbiotic conditions such as atopic dermatitis (AD), eczema, etc. there are significant aberrations of skin pH, along with a higher level of Staphylococcus aureus compared to the commensal Staphylococcus epidermidis on skin. To understand the effect of pH on the relative growth of S. epidermidis and S. aureus, we carried out simple in vitro growth kinetic studies of the individual microbes under varying pH c...
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Microbial dysbiosis with increased Staphylococcus aureus (S. aureus) colonization on the skin is a hallmark of atopic dermatitis (AD), however most microbiome studies focus on bacteria in the flexures and the mic...
Source: BMC Microbiology - Category: Microbiology Authors: Tags: Research Source Type: research
The approval is for the treatment of non-immunocompromised patients aged 12 years and older with mild to moderate atopic dermatitis.FDA Approvals
Source: Medscape Internal Medicine Headlines - Category: Internal Medicine Tags: Dermatology News Alert Source Type: news
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