Single-pulse stimulation of cerebellar nuclei stops epileptic thalamic activity
Epileptic (absence) seizures in cerebral cortex can be stopped by pharmacological and optogenetic stimulation of the cerebellar nuclei (CN) neurons that innervate the thalamus. However, it is unclear how such stimulation can modify underlying thalamo-cortical oscillations.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Oscar H.J. Eelkman Rooda, Lieke Kros, Sade J. Faneyte, Peter J. Holland, Simona V. Gornati, Huub J. Poelman, Nico A. Jansen, Else A. Tolner, Arn M.J.M. van den Maagdenberg, Chris I. De Zeeuw, Freek E. Hoebeek Source Type: research