CTRP3 promotes TNF- α-induced apoptosis and barrier dysfunction in salivary epithelial cells

CONCLUSIONS: These findings suggest that the salivary glands are a novel source of CTRP3 synthesis and secretion. CTRP3 might promote TNF-α-induced cell apoptosis through the TNFR1-mediated complex II pathway.PMID:33991612 | DOI:10.1016/j.cellsig.2021.110042

Source: Cellular Signalling - May 15, 2021 Category: Cytology Authors: Mei Mei Ling-Han Qu Xin Cong Yan Zhang Ruo-Lan Xiang Guang-Yan Yu Jia-Zeng Su Li-Ling Wu Source Type: research