Study finds MDMA-assisted therapy to be safe and highly effective to treat severe PTSD
We report the findings of a randomized, double-blind, placebo-controlled, multi-site phase 3 clinical trial (NCT03537014) to test the efficacy and safety of 3,4‑methylenedioxymethamphetamine (MDMA)-assisted therapy for the treatment of patients with severe PTSD, including those with common comorbidities such as dissociation, depression, a history of alcohol and substance use disorders, and childhood trauma. After psychiatric medication washout, participants (n=90) were randomized 1:1 to receive manualized therapy with MDMA or with placebo, combined with three preparatory and nine integrative therapy sessions … These data indicate that, compared with manualized therapy with inactive placebo, MDMA-assisted therapy is highly efficacious in individuals with severe PTSD, and treatment is safe and well-tolerated, even in those with comorbidities. We conclude that MDMA-assisted therapy represents a potential breakthrough treatment that merits expedited clinical evaluation.
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Source: SharpBrains - Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Clinical-Trial Ecstasy MDMA MDMA-assisted therapy methylenedioxymethamphetamine Molly post-traumatic-stress-disorder psychedelics Psychotherapy PTSD severe PTSD Source Type: blogs
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