Plain packaging 'may help smokers to cut down'

Conclusion This small study showed that priming adult smokers with a picture of a branded cigarette packet causes more of them to seek cigarettes compared with unbranded cigarettes – around 10% more. But this study has problems, meaning we can't really rely on its findings. The biggest of these was fully acknowledged by the study authors themselves. Professor Marcus Munafò, a co-author of the study, explained: "The experimental procedure only modelled the ability of pack stimuli to promote a cigarette-seeking choice. In the natural environment, smoking may be governed by a whole range of factors, including tobacco withdrawal, the presence of other people smoking, time of day, and so on. It is not clear to what extent plain packaging will reduce smoking when these other factors are at play.” The biggest real-world experiment is already happening in Australia, where plain packaging was introduced by law in 2012. The wider evidence showing whether plain packaging reduces smoking-related death and disease in adults or children was not discussed in this study, so we cannot comment. Taken on its own, this specific study adds weak evidence to the debate. There may be stronger evidence elsewhere. On this point, the Addiction journal's editor-in-chief, Professor Robert West, said in the BBC article: "All the pieces are building the same picture, which is that it is going to have a reduction; none of the studies are pointing in the other direction....
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Cancer Medical practice Mental health Source Type: news

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Breast cancer is the leading diagnosed cancer for women globally. Evolution of breast cancer in tumorigenesis, metastasis and treatment resistance appears to be driven by the aberrant gene expression and protein degradation encoded by the cancer genomes. The uncontrolled cancer growth relies on these cellular events, thus constituting the cancerous programs and rendering the addiction towards them. These programs are likely the potential anticancer biomarkers for Personalized Medicine of breast cancer. This review intends to delineate the impact of the CRSPR/Cas-mediated genome editing in identification and validation of t...
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Conclusions: The cells rely more on glucose/gltamine have a stronger sensitivity to glucose/glutamine depletion or glycolysis/ glutaminolysis inhibition and a lessened sensitivity to glutaminolysis/glycolysis inhibitors. To target tumor metabolism based on metabolic characteristics may provide a new therapeutic strategy for the treatment of B cell lymphoma.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Paper Source Type: research
There have been many studies on alcohol and its impact on health, but the relationship is not fully understood. A new, large-scale study investigates.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news
(University of Liege) Researchers have revealed that malignant melanoma can reprogram their protein synthesis machinery and become addicted to a new family of enzymes that modify transfer RNAs during acquired resistance. The inhibition of these molecules synergies with targeted therapies to produce a strong anti-tumoral effect. These new findings will be key in the development of improved diagnostic tools and melanoma treatment.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Conclusions: The treatment algorithm for EGFR mutation is changing with the proven efficacy of osimertinib for the acquired T790M mutation. All patients taking first- or second-generation epidermal growth factor receptor tyrosine kinase inhibitors must be tested. The treatment algorithm for ALK rearrangement has changed with the proven superiority of alectinib compared with crizotinib in the first-line setting. The approval of crizotinib for ROS1 rearrangements now means that patients also must be tested for that mutation. The biomarker for checkpoint inhibitors continues to be PD-L1 by immunohistochemistry stain, but whet...
Source: Current Oncology - Category: Cancer & Oncology Tags: Curr Oncol Source Type: research
Efforts to improve treatment of pain using opioids have to adequately take into account their therapeutic shortcomings which involve addictiveness. While there are no signs of an “opioid epidemic” in Germany s...
Source: BMC Family Practice - Category: Primary Care Authors: Tags: Research article Source Type: research
NEW YORK (CBS Local/CBS News) – Smoking in the U.S. has hit another all-time low. About 14 percent of U.S adults admit to being smokers last year, down from about 16 percent in 2016, government figures from the CDC show. There hadn’t been much change the previous two years, but it’s been clear there’s been a general decline and the new figures show it’s continuing, according to K. Michael Cummings of the tobacco research program at Medical University of South Carolina. “Everything is pointed in the right direction,” including falling cigarette sales and other indicators, Cummi...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Local TV Smoking talkers Source Type: news
Authors: Türker Şener L, Güven C, Şener A, Adin Çinar S, Solakoğlu S, Albeniz I Abstract Breast cancer is the most common type of cancer in females and the second most common cause of cancer mortality after lung cancer. Cancer stem cells represent a novel approach to target cancer and reduce cancer recurrence and metastasis. Many patients with breast cancer continue to smoke after receiving their diagnosis. Nicotine is a key factor in tobacco addiction and also changes some cellular functions, such as activation of mitogenic pathways, angiogenesis and cell proliferation. In the present study, th...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Since early 90  s platinum-based chemotherapy has been the mainstay of treatment for metastatic Non Small Cell Lung Cancer (NSCLC) (Non-small Cell Lung Cancer Collaborative Group, 1995; Schiller et al., 2002). However, during the last two decades front line treatment of metastatic NSCLC has profoundly changed mo ving from the old “one size fits all” concept to a “histology-based” approach and then, for a small subgroup of patients (i.e. EGFR mutated and ALK-rearranged NSCLCs), to a “molecularly-selected” one (Russo et al., 2015).
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research
Maybe this is the last in my series of dander-raising essays, as recent national and world events have most definitely left so many of us with a raging case of TDS. (Trump Derangement Syndrome, look it up it's a thing).So many damned browser tabs open. So little time.Or maybe not. Who knows. Where are all these suicides coming from?My editor keeps telling me, " don't let it make you paralytic. " Hey, I'm trying.Just sensing a kind of coalescence in all the corruption our bloggers keep writing about. How do we even differentiate these activities across so many sectors of society. We were going to see our swamp dra...
Source: Health Care Renewal - Category: Health Management Source Type: blogs
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