Impact of uORFs in mediating regulation of translation in stress conditions

A large fraction of genes contains upstream ORFs (uORFs) in the 5 ′ untranslated region (5’UTR). The translation of uORFs can inhibit the translation of the main coding sequence, for example by causing prematur...

Source: BMC Cell Biology - May 16, 2021 Category: Cytology Authors: Simone G. Moro, Cedric Hermans, Jorge Ruiz-Orera and M. Mar Alb à Tags: Research Source Type: research