Autophagy and PTEN in DNA damage-induced senescence

We present experimental evidence obtained with tumor cells, with a prime focus on two models of cancer, prostate and lung. A better understanding of mechanisms associated with DNA damage-induced cellular senescence is central to fully exploit the potential of DNA-damaging agents against cancer.PMID:33858598 | DOI:10.1016/bs.acr.2021.01.006
Source: Advances in Cancer Research - Category: Cancer & Oncology Authors: Source Type: research