Extended survival and reproductive potential of single-sex male and female Schistosoma japonicum within definitive hosts

Int J Parasitol. 2021 Apr 24:S0020-7519(21)00143-0. doi: 10.1016/j.ijpara.2021.03.005. Online ahead of print.ABSTRACTSchistosomiasis is caused by dioecious helminths of the genus Schistosoma. Recent work indicated that unpaired female and male schistosomes can survive within their definitive host for at least 1 year, although the viability or fertility of these worms after subsequent pairing remained untested. We performed two experiments on laboratory mice, one with female Schistosoma japonicum exposure first and male schistosomes second and another vice versa. After surviving as single-sex unpaired forms for up to 1 year, 58.5% of male and 70% of female schistosomes were able to mate and produce viable eggs. This highlights an additional biological challenge in achieving elimination of schistosomiasis.PMID:33905765 | DOI:10.1016/j.ijpara.2021.03.005
Source: International Journal for Parasitology - Category: Parasitology Authors: Source Type: research