Molecules, Vol. 26, Pages 2926: An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill

Molecules, Vol. 26, Pages 2926: An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill
Molecules doi: 10.3390/molecules26102926
Authors:
Alexandra G. Durán
M. Teresa Gutiérrez
Francisco J. R. Mejías
José M. G. Molinillo
Francisco A. Macías

Annona cherimola Mill., or the custard apple, is one of the species belonging to the Annonaceae family, is widely used in traditional medicine, and has been reported to be a valuable source of bioactive compounds. A unique class of secondary metabolites derived from this family are Annonaceous acetogenins, lipophilic polyketides considered to be amongst the most potent antitumor compounds. This review provides an overview of the chemical diversity, isolation procedures, bioactivity, modes of application and synthetic derivatives of acetogenins from A. cherimola Mill.

Source: Molecules - May 14, 2021 Category: Chemistry Authors: Alexandra G. Dur án M. Teresa Guti érrez Francisco J. R. Mej ías Jos é M. G. Molinillo Francisco A. Mac ías Tags: Review Source Type: research