Evaluating the value of Amphiregulin, Phosphatase and Tensin Homologue (PTEN) and P21 Expression for Anti-EGFR Treatment in Metastatic Colorectal Carcinoma

CONCLUSION: High Amphiregulin and PTEN expression levels and low P21 expression levels were associated with better response to anti-EGFR therapy and improved survival outcome. They might be considered predictive markers of response to anti-EGFR therapy in mCRC.<br /> <br />.PMID:33906293 | DOI:10.31557/APJCP.2021.22.4.1025

Source: Asian Pacific Journal of Cancer Prevention - April 28, 2021 Category: Cancer & Oncology Authors: Ahmed Ali Obaya Amrallah A Mohammed Hanaa Rashied Adel Mahmoud Morsy Gamal Osman Ahmed S Allam Ahmed M Elsayed Ola A Harb Walid S H Elsayed Source Type: research