Effect of < em > Porphyromonas gingivalis < /em > lipopolysaccharide on calcification of human umbilical artery smooth muscle cells co-cultured with human periodontal ligament cells

In conclusion, co-culture with HPDLCs increased the effect of Pg-LPS to stimulate the calcification of HUASMCs. It was suggested that besides the inflammation, periodontitis may promote the occurrence of vascular calcification. The study indicated that periodontal treatment of subgingival scaling to reduce and/or control Porphyromonas gingivalis may decrease the occurrence or severity of vascular calcification.PMID:33968185 | PMC:PMC8097230 | DOI:10.3892/etm.2021.10087
Source: Experimental and Therapeutic Medicine - Category: General Medicine Authors: Source Type: research