A new polarized fluorescent probe for revealing architectural dynamics of living cells

(Tokyo Medical and Dental University) Researchers from TMDU, collaborating with scientists from MBL and RIKEN, developed a new probe, POLArIS, for real-time live-cell imaging that reveals the orientation of molecules and is expected to be applicable to a wide range of cell types and specimens. They tested POLArIS in starfish early embryos and discovered the existence of a new F-actin cellular architecture, FLARE, extending alongside the astral microtubules to the cell cortex. This may provide answers to some of the most fundamental questions regarding cell division.

Source: EurekAlert! - Biology - May 13, 2021 Category: Biology Source Type: news